Structural basis of human transcription–DNA repair coupling
Structural basis of human transcription–DNA repair coupling
About this item
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Transcription-coupled DNA repair removes bulky DNA lesions from the genome
1
,
2
and protects cells against ultraviolet (UV) irradiation
3
. Transcription-coupled DNA repair begins when RNA polymerase II (Pol II) stalls at a DNA lesion and recruits the Cockayne syndrome protein CSB, the E3 ubiquitin ligase, CRL4
CSA
and UV-s...
Alternative Titles
Full title
Structural basis of human transcription–DNA repair coupling
Authors, Artists and Contributors
Author / Creator
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8514338
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8514338
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03906-4
