Log in to save to my catalogue
Log in to save to my catalogue

Complex genetic signatures in immune cells underlie autoimmunity and inform therapy

| Ask | Become a Library member

Complex genetic signatures in immune cells underlie autoimmunity and inform therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8517961

Complex genetic signatures in immune cells underlie autoimmunity and inform therapy

About this item

Publication information

Publisher

New York: Nature Publishing Group US

Subjects

More information

Scope and Contents

Contents

We report on the influence of ~22 million variants on 731 immune cell traits in a cohort of 3,757 Sardinians. We detected 122 significant (
P
 < 1.28 × 10
−11
) independent association signals for 459 cell traits at 70 loci (53 of them novel) identifying several molecules and mechanisms involved in cell regulation. Furthermore, 53 signa...

Alternative Titles

Full title

Complex genetic signatures in immune cells underlie autoimmunity and inform therapy

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8517961

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8517961

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/s41588-020-0684-4

How to access this item

Log in as a Library member

View record in Gale

About resource

View in old catalogue

Connecting people and collections