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Metformin exerts a synergistic effect with venetoclax by downregulating Mcl-1 protein in acute myelo...

Metformin exerts a synergistic effect with venetoclax by downregulating Mcl-1 protein in acute myelo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8518002

Metformin exerts a synergistic effect with venetoclax by downregulating Mcl-1 protein in acute myeloid leukemia

About this item

Full title

Metformin exerts a synergistic effect with venetoclax by downregulating Mcl-1 protein in acute myeloid leukemia

Publisher

Wyoming: Ivyspring International Publisher Pty Ltd

Journal title

Journal of Cancer, 2021-01, Vol.12 (22), p.6727-6739

Language

English

Formats

Publication information

Publisher

Wyoming: Ivyspring International Publisher Pty Ltd

More information

Scope and Contents

Contents

Background: Recently, one of the specific BH3-mimetics, Venetoclax has been approved by FDA providing new options for newly diagnosed AML patient especially who are unfitted to receive conventional chemotherapy. Though the clinical success of venetoclax has been achieved in clinical outcomes such as complete remission (CR) and overall survival. Acq...

Alternative Titles

Full title

Metformin exerts a synergistic effect with venetoclax by downregulating Mcl-1 protein in acute myeloid leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8518002

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8518002

Other Identifiers

ISSN

1837-9664

E-ISSN

1837-9664

DOI

10.7150/jca.60208

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