Advanced Maternal Age‐associated SIRT1 Deficiency Compromises Trophoblast Epithelial−Mesenchymal Tra...
Advanced Maternal Age‐associated SIRT1 Deficiency Compromises Trophoblast Epithelial−Mesenchymal Transition through an Increase in Vimentin Acetylation
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Author / Creator
Xiong, Liling , Ye, Xuan , Chen, Zhi , Fu, Huijia , Li, Sisi , Xu, Ping , Yu, Jiaxiao , Wen, Li , Gao, Rufei , Fu, Yong , Qi, Hongbo , Kilby, Mark D. , Saffery, Richard , Baker, Philip N. and Tong, Chao
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Scope and Contents
Contents
Advanced maternal age (AMA) pregnancies are rapidly increasing and are associated with aberrant trophoblast cell function, poor placentation, and unfavorable pregnancy outcomes, presumably due to premature placental senescence. SIRT1 is an NAD+‐dependent deacetylase with well‐known antiaging effects, but its connection with placental senescence is...
Alternative Titles
Full title
Advanced Maternal Age‐associated SIRT1 Deficiency Compromises Trophoblast Epithelial−Mesenchymal Transition through an Increase in Vimentin Acetylation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8520724
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8520724
Other Identifiers
ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.13491
