Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation
Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation
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Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Formation of NO by endothelial NOS (eNOS) is a central process in the homeostatic regulation of vascular functions including blood pressure regulation, and fluid shear stress exerted by the flowing blood is a main stimulus of eNOS activity. Previous work has identified several mechanosensing and -transducing processes in endothelial cells, which me...
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Full title
Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8553558
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8553558
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI145734
