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Developmental window of vulnerability to white matter injury driven by sublethal intermittent hypoxe...

Developmental window of vulnerability to white matter injury driven by sublethal intermittent hypoxe...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8566320

Developmental window of vulnerability to white matter injury driven by sublethal intermittent hypoxemia

About this item

Full title

Developmental window of vulnerability to white matter injury driven by sublethal intermittent hypoxemia

Publisher

New York: Nature Publishing Group US

Journal title

Pediatric research, 2022-05, Vol.91 (6), p.1383-1390

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Background
In the developing brain, the death of immature oligodendrocytes (OLs) has been proposed to explain a developmental window for vulnerability to white matter injury (WMI). However, in neonatal mice, chronic sublethal intermittent hypoxia (IH) recapitulates the phenotype of diffuse WMI without affecting cellular viability. This work dete...

Alternative Titles

Full title

Developmental window of vulnerability to white matter injury driven by sublethal intermittent hypoxemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8566320

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8566320

Other Identifiers

ISSN

0031-3998

E-ISSN

1530-0447

DOI

10.1038/s41390-021-01555-x

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