B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity
B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity
About this item
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Author / Creator
Zhang, Baihao , Vogelzang, Alexis , Miyajima, Michio , Sugiura, Yuki , Wu, Yibo , Chamoto, Kenji , Nakano, Rei , Hatae, Ryusuke , Menzies, Rosemary J. , Sonomura, Kazuhiro , Hojo, Nozomi , Ogawa, Taisaku , Kobayashi, Wakana , Tsutsui, Yumi , Yamamoto, Sachiko , Maruya, Mikako , Narushima, Seiko , Suzuki, Keiichiro , Sugiya, Hiroshi , Murakami, Kosaku , Hashimoto, Motomu , Ueno, Hideki , Kobayashi, Takashi , Ito, Katsuhiro , Hirano, Tomoko , Shiroguchi, Katsuyuki , Matsuda, Fumihiko , Suematsu, Makoto , Honjo, Tasuku and Fagarasan, Sidonia
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Small, soluble metabolites not only are essential intermediates in intracellular biochemical processes, but can also influence neighbouring cells when released into the extracellular milieu
1
–
3
. Here we identify the metabolite and neurotransmitter GABA as a candidate signalling molecule synthesized and secreted by activated B cells a...
Alternative Titles
Full title
B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity
Authors, Artists and Contributors
Author / Creator
Vogelzang, Alexis
Miyajima, Michio
Sugiura, Yuki
Wu, Yibo
Chamoto, Kenji
Nakano, Rei
Hatae, Ryusuke
Menzies, Rosemary J.
Sonomura, Kazuhiro
Hojo, Nozomi
Ogawa, Taisaku
Kobayashi, Wakana
Tsutsui, Yumi
Yamamoto, Sachiko
Maruya, Mikako
Narushima, Seiko
Suzuki, Keiichiro
Sugiya, Hiroshi
Murakami, Kosaku
Hashimoto, Motomu
Ueno, Hideki
Kobayashi, Takashi
Ito, Katsuhiro
Hirano, Tomoko
Shiroguchi, Katsuyuki
Matsuda, Fumihiko
Suematsu, Makoto
Honjo, Tasuku
Fagarasan, Sidonia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8599023
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8599023
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-04082-1
