Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and imm...
Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial
About this item
Full title
Author / Creator
Forde, Patrick M. , Anagnostou, Valsamo , Sun, Zhuoxin , Dahlberg, Suzanne E. , Kindler, Hedy L. , Niknafs, Noushin , Purcell, Thomas , Santana-Davila, Rafael , Dudek, Arkadiusz Z. , Borghaei, Hossein , Lanis, Mara , Belcaid, Zineb , Smith, Kellie N. , Balan, Archana , White, James R. , Cherry, Christopher , Ashok Sivakumar, I. K. , Shao, Xiaoshan M. , Chan, Hok Yee , Singh, Dipika , Thapa, Sampriti , Illei, Peter B. , Pardoll, Drew M. , Karchin, Rachel , Velculescu, Victor E. , Brahmer, Julie R. and Ramalingam, Suresh S.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Mesothelioma is a rare and fatal cancer with limited therapeutic options until the recent approval of combination immune checkpoint blockade. Here we report the results of the phase 2 PrE0505 trial (
NCT02899195
) of the anti-PD-L1 antibody durvalumab plus platinum-pemetrexed chemotherapy for 55 patients with previously untreated, unresectabl...
Alternative Titles
Full title
Durvalumab with platinum-pemetrexed for unresectable pleural mesothelioma: survival, genomic and immunologic analyses from the phase 2 PrE0505 trial
Authors, Artists and Contributors
Author / Creator
Anagnostou, Valsamo
Sun, Zhuoxin
Dahlberg, Suzanne E.
Kindler, Hedy L.
Niknafs, Noushin
Purcell, Thomas
Santana-Davila, Rafael
Dudek, Arkadiusz Z.
Borghaei, Hossein
Lanis, Mara
Belcaid, Zineb
Smith, Kellie N.
Balan, Archana
White, James R.
Cherry, Christopher
Ashok Sivakumar, I. K.
Shao, Xiaoshan M.
Chan, Hok Yee
Singh, Dipika
Thapa, Sampriti
Illei, Peter B.
Pardoll, Drew M.
Karchin, Rachel
Velculescu, Victor E.
Brahmer, Julie R.
Ramalingam, Suresh S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8604731
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8604731
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-021-01541-0
