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Landscape of prognostic signatures and immunogenomics of the AXL/GAS6 axis in renal cell carcinoma

Landscape of prognostic signatures and immunogenomics of the AXL/GAS6 axis in renal cell carcinoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8608819

Landscape of prognostic signatures and immunogenomics of the AXL/GAS6 axis in renal cell carcinoma

About this item

Full title

Landscape of prognostic signatures and immunogenomics of the AXL/GAS6 axis in renal cell carcinoma

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2021-11, Vol.125 (11), p.1533-1543

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Background
Cabozantinib is an oral tyrosine kinase inhibitor in renal cell carcinoma (RCC), whose targets include oncogenic AXL and unique ligand GAS6. Critical gaps in basic knowledge need to be addressed to devise an exclusive biomarker and candidate when targeting the AXL/GAS6 axis.
Methods
To clarify the effects of the AXL/GAS6 axis on...

Alternative Titles

Full title

Landscape of prognostic signatures and immunogenomics of the AXL/GAS6 axis in renal cell carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8608819

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8608819

Other Identifiers

ISSN

0007-0920

E-ISSN

1532-1827

DOI

10.1038/s41416-021-01559-8

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