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Activation of PTH1R alleviates epididymitis and orchitis through Gq and β-arrestin-1 pathways

Activation of PTH1R alleviates epididymitis and orchitis through Gq and β-arrestin-1 pathways

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8609314

Activation of PTH1R alleviates epididymitis and orchitis through Gq and β-arrestin-1 pathways

About this item

Full title

Activation of PTH1R alleviates epididymitis and orchitis through Gq and β-arrestin-1 pathways

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2021-11, Vol.118 (45), p.1-11

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Inflammation in the epididymis and testis contributes significantly to male infertility. Alternative therapeutic avenues treating epididymitis and orchitis are expected since current therapies using antibiotics have limitations associated to side effects and are commonly ineffective for inflammation due to nonbacterial causes. Here, we demonstrated...

Alternative Titles

Full title

Activation of PTH1R alleviates epididymitis and orchitis through Gq and β-arrestin-1 pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8609314

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8609314

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2107363118

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