Architecture and assembly mechanism of native glycine receptors
Architecture and assembly mechanism of native glycine receptors
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Glycine receptors (GlyRs) are pentameric, ‘Cys-loop’ receptors that form chloride-permeable channels and mediate fast inhibitory signalling throughout the central nervous system
1
,
2
. In the spinal cord and brainstem, GlyRs regulate locomotion and cause movement disorders when mutated
2
,
3
. However, the stoichiometry of...
Alternative Titles
Full title
Architecture and assembly mechanism of native glycine receptors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8647860
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8647860
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-04022-z
