Hierarchical regulation of the resting and activated T cell epigenome by major transcription factor...
Hierarchical regulation of the resting and activated T cell epigenome by major transcription factor families
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
T cell activation, a key early event in the adaptive immune response, is subject to elaborate transcriptional control. In the present study, we examined how the activities of eight major transcription factor (TF) families are integrated to shape the epigenome of naive and activated CD4 and CD8 T cells. By leveraging extensive polymorphisms in evolu...
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Full title
Hierarchical regulation of the resting and activated T cell epigenome by major transcription factor families
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8712421
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8712421
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-021-01086-x