N6-methyladenosine (m⁶A) depletion regulates pluripotency exit by activating signaling pathways in e...
N6-methyladenosine (m⁶A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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N6-methyladenosine (m⁶A) deposition on messenger RNA (mRNA) controls embryonic stem cell (ESC) fate by regulating the mRNA stabilities of pluripotency and lineage transcription factors (TFs) [P. J. Batista et al., Cell Stem Cell 15, 707–719 (2014); Y. Wang et al., Nat. Cell Biol. 16, 191–198 (2014); and S. Geula et al., Science 347, 1002–1006 (2015...
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Full title
N6-methyladenosine (m⁶A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8713808
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8713808
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2105192118
