RSL3 Drives Ferroptosis through NF-κB Pathway Activation and GPX4 Depletion in Glioblastoma
RSL3 Drives Ferroptosis through NF-κB Pathway Activation and GPX4 Depletion in Glioblastoma
About this item
Full title
Author / Creator
Li, Shengbiao , He, Yuping , Chen, Kexin , Sun, Jiaojiao , Zhang, Lulu , He, Yaxin , Yu, Hong and Li, Qiuhong
Publisher
United States: Hindawi
Journal title
Language
English
Formats
Publication information
Publisher
United States: Hindawi
Subjects
More information
Scope and Contents
Contents
Glioblastoma, the most aggressive form of malignant glioma, is very difficult to treat because of its aggressively invasive nature and high recurrence rates. RAS-selective lethal 3 (RSL3), a well-known inhibitor of glutathione peroxidase 4 (GPX4), could effectively induce oxidative cell death in glioblastoma cells through ferroptosis, and several s...
Alternative Titles
Full title
RSL3 Drives Ferroptosis through NF-κB Pathway Activation and GPX4 Depletion in Glioblastoma
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8720588
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8720588
Other Identifiers
ISSN
1942-0900
E-ISSN
1942-0994
DOI
10.1155/2021/2915019
