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A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer...

A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8727571

A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer cells

About this item

Full title

A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer cells

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2022-01, Vol.126 (1), p.109-119

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Background
KLF5 plays a crucial role in stem cells of colorectum in cooperation with
Lgr5
gene. In this study, we aimed to explicate a regulatory mechanism of the
KLF5
gene product from a view of three-dimensional genome structure in colorectal cancer (CRC).
Methods
In vitro engineered DNA-binding molecule-mediated chromatin im...

Alternative Titles

Full title

A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8727571

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8727571

Other Identifiers

ISSN

0007-0920

E-ISSN

1532-1827

DOI

10.1038/s41416-021-01579-4

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