A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer...
A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer cells
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
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Scope and Contents
Contents
Background
KLF5 plays a crucial role in stem cells of colorectum in cooperation with
Lgr5
gene. In this study, we aimed to explicate a regulatory mechanism of the
KLF5
gene product from a view of three-dimensional genome structure in colorectal cancer (CRC).
Methods
In vitro engineered DNA-binding molecule-mediated chromatin im...
Alternative Titles
Full title
A stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer cells
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8727571
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8727571
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-021-01579-4