Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metaboli...
Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation
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Author / Creator
Longchamps, R. J. , Yang, S. Y. , Castellani, C. A. , Shi, W. , Lane, J. , Grove, M. L. , Bartz, T. M. , Sarnowski, C. , Liu, C. , Burrows, K. , Guyatt, A. L. , Gaunt, T. R. , Kacprowski, T. , Yang, J. , De Jager, P. L. , Yu, L. , Bergman, A. , Xia, R. , Fornage, M. , Feitosa, M. F. , Wojczynski, M. K. , Kraja, A. T. , Province, M. A. , Amin, N. , Rivadeneira, F. , Tiemeier, H. , Uitterlinden, A. G. , Broer, L. , Van Meurs, J. B. J. , Van Duijn, C. M. , Raffield, L. M. , Lange, L. , Rich, S. S. , Lemaitre, R. N. , Goodarzi, M. O. , Sitlani, C. M. , Mak, A. C. Y. , Bennett, D. A. , Rodriguez, S. , Murabito, J. M. , Lunetta, K. L. , Sotoodehnia, N. , Atzmon, G. , Ye, K. , Barzilai, N. , Brody, J. A. , Psaty, B. M. , Taylor, K. D. , Rotter, J. I. , Boerwinkle, E. , Pankratz, N. and Arking, D. E.
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Mitochondrial DNA copy number (mtDNA-CN) measured from blood specimens is a minimally invasive marker of mitochondrial function that exhibits both inter-individual and intercellular variation. To identify genes involved in regulating mitochondrial function, we performed a genome-wide association study (GWAS) in 465,809 White individuals from the Co...
Alternative Titles
Full title
Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation
Authors, Artists and Contributors
Author / Creator
Yang, S. Y.
Castellani, C. A.
Shi, W.
Lane, J.
Grove, M. L.
Bartz, T. M.
Sarnowski, C.
Liu, C.
Burrows, K.
Guyatt, A. L.
Gaunt, T. R.
Kacprowski, T.
Yang, J.
De Jager, P. L.
Yu, L.
Bergman, A.
Xia, R.
Fornage, M.
Feitosa, M. F.
Wojczynski, M. K.
Kraja, A. T.
Province, M. A.
Amin, N.
Rivadeneira, F.
Tiemeier, H.
Uitterlinden, A. G.
Broer, L.
Van Meurs, J. B. J.
Van Duijn, C. M.
Raffield, L. M.
Lange, L.
Rich, S. S.
Lemaitre, R. N.
Goodarzi, M. O.
Sitlani, C. M.
Mak, A. C. Y.
Bennett, D. A.
Rodriguez, S.
Murabito, J. M.
Lunetta, K. L.
Sotoodehnia, N.
Atzmon, G.
Ye, K.
Barzilai, N.
Brody, J. A.
Psaty, B. M.
Taylor, K. D.
Rotter, J. I.
Boerwinkle, E.
Pankratz, N.
Arking, D. E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758627
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758627
Other Identifiers
ISSN
0340-6717
E-ISSN
1432-1203
DOI
10.1007/s00439-021-02394-w
