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Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in sin...

Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in sin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8763625

Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells

About this item

Full title

Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2021-10, Vol.39 (10), p.1246-1258

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Recent technological advances have enabled massively parallel chromatin profiling with scATAC-seq (single-cell assay for transposase accessible chromatin by sequencing). Here we present ATAC with select antigen profiling by sequencing (ASAP-seq), a tool to simultaneously profile accessible chromatin and protein levels. Our approach pairs sparse scA...

Alternative Titles

Full title

Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8763625

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8763625

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/s41587-021-00927-2

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