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Toll-like receptor 4-mediated necroptosis in the development of necrotizing enterocolitis

Toll-like receptor 4-mediated necroptosis in the development of necrotizing enterocolitis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8770135

Toll-like receptor 4-mediated necroptosis in the development of necrotizing enterocolitis

About this item

Full title

Toll-like receptor 4-mediated necroptosis in the development of necrotizing enterocolitis

Publisher

New York: Nature Publishing Group US

Journal title

Pediatric research, 2022-01, Vol.91 (1), p.73-82

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Background
Dramatic intestinal epithelial cell death leading to barrier dysfunction is one of the mechanism of neonatal necrotizing enterocolitis (NEC), in which Toll-like receptor 4 (TLR4) plays a pivotal role. This study explored the role of necroptosis, a drastic way of cell death in NEC.
Methods
The expression of necroptotic proteins w...

Alternative Titles

Full title

Toll-like receptor 4-mediated necroptosis in the development of necrotizing enterocolitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8770135

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8770135

Other Identifiers

ISSN

0031-3998

E-ISSN

1530-0447

DOI

10.1038/s41390-021-01457-y

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