Poly (ADP-ribose) polymerase 1 (PARP1) inhibition promotes pulmonary metastasis of osteosarcoma by b...
Poly (ADP-ribose) polymerase 1 (PARP1) inhibition promotes pulmonary metastasis of osteosarcoma by boosting ezrin phosphorylation
About this item
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Author / Creator
Li, Fangfei , Wu, Xiaoqiu , Fu, Xuekun , Liu, Jin , Song, Wangze , Xiao, Gary Guishan , Lu, Aiping and Zhang, Ge
Publisher
Australia: Ivyspring International Publisher Pty Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Scope and Contents
Contents
Due to the large proportion of BRCA deficiency and chromosomal instability in OS patients, poly (ADP-ribose) polymerase inhibitors (PARPi) could be an effective strategy for anti-OS therapy. In two orthotopic OS mouse models, we discovered that although PARPi had inhibitory effect on the growth of the orthotopic OS tumors regardless of BRCA deficie...
Alternative Titles
Full title
Poly (ADP-ribose) polymerase 1 (PARP1) inhibition promotes pulmonary metastasis of osteosarcoma by boosting ezrin phosphorylation
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8771856
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8771856
Other Identifiers
ISSN
1449-2288
E-ISSN
1449-2288
DOI
10.7150/ijbs.58784
