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Identification and Characterization of an Exonic Duplication in PALB2 in a Man with Synchronous Brea...

Identification and Characterization of an Exonic Duplication in PALB2 in a Man with Synchronous Brea...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8775416

Identification and Characterization of an Exonic Duplication in PALB2 in a Man with Synchronous Breast and Prostate Cancer

About this item

Full title

Identification and Characterization of an Exonic Duplication in PALB2 in a Man with Synchronous Breast and Prostate Cancer

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2022-01, Vol.23 (2), p.667

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

(partner and localizer of
), as indicated by its name, is a
-interacting protein that plays an important role in homologous recombination (HR) and DNA double-strand break (DSB) repair. While pathogenic variants of
have been well proven to confer an increased risk of breast cancer, data on its involvement in prostate cancer (PrC) have not b...

Alternative Titles

Full title

Identification and Characterization of an Exonic Duplication in PALB2 in a Man with Synchronous Breast and Prostate Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8775416

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8775416

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms23020667

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