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CD169⁺ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling

CD169⁺ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8784161

CD169⁺ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling

About this item

Full title

CD169⁺ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2022-01, Vol.119 (3), p.1-9

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

CD169⁺ macrophages reside in lymph node (LN) and spleen and play an important role in the immune defense against pathogens. As resident macrophages, they are responsive to environmental cues to shape their tissue-specific identity. We have previously shown that LN CD169⁺ macrophages require RANKL for formation of their niche and their differentiati...

Alternative Titles

Full title

CD169⁺ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8784161

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8784161

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2108540119

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