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Immunogenicity and Reactogenicity of Vaccine Boosters after Ad26.COV2.S Priming

Immunogenicity and Reactogenicity of Vaccine Boosters after Ad26.COV2.S Priming

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8796791

Immunogenicity and Reactogenicity of Vaccine Boosters after Ad26.COV2.S Priming

About this item

Full title

Immunogenicity and Reactogenicity of Vaccine Boosters after Ad26.COV2.S Priming

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2022-03, Vol.386 (10), p.951-963

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

A trial involving 434 participants examined the effects of no boosting or of boosting with one of the three approved Covid-19 vaccines — Ad26.COV2.S, mRNA-1273, or BNT162b2 — 3 months after the primary vaccination. All the vaccines increased neutralizing-antibody levels and T-cell responses, but the increases with the mRNA vaccines were higher.

Alternative Titles

Full title

Immunogenicity and Reactogenicity of Vaccine Boosters after Ad26.COV2.S Priming

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8796791

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8796791

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa2116747

How to access this item