A molecular single-cell lung atlas of lethal COVID-19
A molecular single-cell lung atlas of lethal COVID-19
About this item
Full title
Author / Creator
Melms, Johannes C. , Biermann, Jana , Huang, Huachao , Wang, Yiping , Nair, Ajay , Tagore, Somnath , Katsyv, Igor , Rendeiro, André F. , Amin, Amit Dipak , Schapiro, Denis , Frangieh, Chris J. , Luoma, Adrienne M. , Filliol, Aveline , Fang, Yinshan , Ravichandran, Hiranmayi , Clausi, Mariano G. , Alba, George A. , Rogava, Meri , Chen, Sean W. , Ho, Patricia , Montoro, Daniel T. , Kornberg, Adam E. , Han, Arnold S. , Bakhoum, Mathieu F. , Anandasabapathy, Niroshana , Suárez-Fariñas, Mayte , Bakhoum, Samuel F. , Bram, Yaron , Borczuk, Alain , Guo, Xinzheng V. , Lefkowitch, Jay H. , Marboe, Charles , Lagana, Stephen M. , Del Portillo, Armando , Tsai, Emily J. , Zorn, Emmanuel , Markowitz, Glen S. , Schwabe, Robert F. , Schwartz, Robert E. , Elemento, Olivier , Saqi, Anjali , Hibshoosh, Hanina , Que, Jianwen and Izar, Benjamin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Respiratory failure is the leading cause of death in patients with severe SARS-CoV-2 infection
1
,
2
, but the host response at the lung tissue level is poorly understood. Here we performed single-nucleus RNA sequencing of about 116,000 nuclei from the lungs of nineteen individuals who died of COVID-19 and underwent rapid autopsy and se...
Alternative Titles
Full title
A molecular single-cell lung atlas of lethal COVID-19
Authors, Artists and Contributors
Author / Creator
Biermann, Jana
Huang, Huachao
Wang, Yiping
Nair, Ajay
Tagore, Somnath
Katsyv, Igor
Rendeiro, André F.
Amin, Amit Dipak
Schapiro, Denis
Frangieh, Chris J.
Luoma, Adrienne M.
Filliol, Aveline
Fang, Yinshan
Ravichandran, Hiranmayi
Clausi, Mariano G.
Alba, George A.
Rogava, Meri
Chen, Sean W.
Ho, Patricia
Montoro, Daniel T.
Kornberg, Adam E.
Han, Arnold S.
Bakhoum, Mathieu F.
Anandasabapathy, Niroshana
Suárez-Fariñas, Mayte
Bakhoum, Samuel F.
Bram, Yaron
Borczuk, Alain
Guo, Xinzheng V.
Lefkowitch, Jay H.
Marboe, Charles
Lagana, Stephen M.
Del Portillo, Armando
Tsai, Emily J.
Zorn, Emmanuel
Markowitz, Glen S.
Schwabe, Robert F.
Schwartz, Robert E.
Elemento, Olivier
Saqi, Anjali
Hibshoosh, Hanina
Que, Jianwen
Izar, Benjamin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8814825
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8814825
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03569-1
