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Design, synthesis, and computational studies of phenylacetamides as antidepressant agents

Design, synthesis, and computational studies of phenylacetamides as antidepressant agents

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8818363

Design, synthesis, and computational studies of phenylacetamides as antidepressant agents

About this item

Full title

Design, synthesis, and computational studies of phenylacetamides as antidepressant agents

Publisher

Cham: Springer International Publishing

Journal title

Molecular diversity, 2022-12, Vol.26 (6), p.3157-3172

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

In the present work, a hit molecule obtained from zinc ‘clean drug-like database’ by systematically performed computational studies was modified chemically to obtain different derivatives (
VS1–VS25
). Structures of synthesized derivatives were confirmed by IR,
1
H-NMR,
13
C-NMR,
13
C-DEPT, MS, and elemental analysis. All th...

Alternative Titles

Full title

Design, synthesis, and computational studies of phenylacetamides as antidepressant agents

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8818363

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8818363

Other Identifiers

ISSN

1381-1991

E-ISSN

1573-501X

DOI

10.1007/s11030-021-10374-5

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