Integrative analysis reveals multiple modes of LXR transcriptional regulation in liver
Integrative analysis reveals multiple modes of LXR transcriptional regulation in liver
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The nuclear receptors liver X receptor (LXR) α and β play crucial roles in hepatic metabolism. Many genes induced in response to pharmacologic LXR agonism have been defined; however, the transcriptional consequences of loss of LXR binding to its genomic targets are less well characterized. Here, we addressed how deletion of both LXRα and LXRβ from...
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Integrative analysis reveals multiple modes of LXR transcriptional regulation in liver
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8851562
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8851562
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2122683119