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Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8866119

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

About this item

Full title

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2022-02, Vol.602 (7898), p.657-663

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The SARS-CoV-2 B.1.1.529 (Omicron) variant contains 15 mutations of the receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies requires immediate investigation. Here we use high-throughput yeast display screening
1
,
2
to determine the profiles of RBD escaping mutations for 247 human anti-RBD neutralizing...

Alternative Titles

Full title

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8866119

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8866119

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-021-04385-3

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