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Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing...

Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8876130

Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases

About this item

Full title

Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2022-02, Vol.25 (2), p.180-190

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Multiple studies indicate that adult male rodents perform better than females on spatial problems and have a lower threshold for long-term potentiation (LTP) of hippocampal CA3-to-CA1 synapses. We report here that, in rodents, prepubescent females rapidly encode spatial information and express low-threshold LTP, whereas age-matched males do not. Th...

Alternative Titles

Full title

Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8876130

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8876130

Other Identifiers

ISSN

1097-6256,1546-1726

E-ISSN

1546-1726

DOI

10.1038/s41593-021-01001-5

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