Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing...
Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Multiple studies indicate that adult male rodents perform better than females on spatial problems and have a lower threshold for long-term potentiation (LTP) of hippocampal CA3-to-CA1 synapses. We report here that, in rodents, prepubescent females rapidly encode spatial information and express low-threshold LTP, whereas age-matched males do not. Th...
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Prepubescent female rodents have enhanced hippocampal LTP and learning relative to males, reversing in adulthood as inhibition increases
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8876130
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8876130
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ISSN
1097-6256,1546-1726
E-ISSN
1546-1726
DOI
10.1038/s41593-021-01001-5