The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin
The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Focal adhesions (FAs) are large, integrin-based protein complexes that link cells to the extracellular matrix (ECM). FAs form only when and where they are necessary to transmit force between the cellular cytoskeleton and the ECM, but how this occurs remains poorly understood. Talin is a 270-kDa adaptor protein that links integrins to filamentous (F...
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Full title
The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8915792
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8915792
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2109329119