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Scaling analysis reveals the mechanism and rates of prion replication in vivo

Scaling analysis reveals the mechanism and rates of prion replication in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8922999

Scaling analysis reveals the mechanism and rates of prion replication in vivo

About this item

Full title

Scaling analysis reveals the mechanism and rates of prion replication in vivo

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2021-04, Vol.28 (4), p.365-372

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Prions consist of pathological aggregates of cellular prion protein and have the ability to replicate, causing neurodegenerative diseases, a phenomenon mirrored in many other diseases connected to protein aggregation, including Alzheimer’s and Parkinson’s diseases. However, despite their key importance in disease, the individual processes governing...

Alternative Titles

Full title

Scaling analysis reveals the mechanism and rates of prion replication in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8922999

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8922999

Other Identifiers

ISSN

1545-9993,1545-9985

E-ISSN

1545-9985

DOI

10.1038/s41594-021-00565-x

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