Human organs-on-chips for disease modelling, drug development and personalized medicine
Human organs-on-chips for disease modelling, drug development and personalized medicine
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The failure of animal models to predict therapeutic responses in humans is a major problem that also brings into question their use for basic research. Organ-on-a-chip (organ chip) microfluidic devices lined with living cells cultured under fluid flow can recapitulate organ-level physiology and pathophysiology with high fidelity. Here, I review how...
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Human organs-on-chips for disease modelling, drug development and personalized medicine
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8951665
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8951665
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ISSN
1471-0056
E-ISSN
1471-0064
DOI
10.1038/s41576-022-00466-9
