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Glucose Metabolism and Aging of Hematopoietic Stem and Progenitor Cells

Glucose Metabolism and Aging of Hematopoietic Stem and Progenitor Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8955027

Glucose Metabolism and Aging of Hematopoietic Stem and Progenitor Cells

About this item

Full title

Glucose Metabolism and Aging of Hematopoietic Stem and Progenitor Cells

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2022-03, Vol.23 (6), p.3028

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Comprehensive proteomics studies of human hematopoietic stem and progenitor cells (HSPC) have revealed that aging of the HSPC compartment is characterized by elevated glycolysis. This is in addition to deregulations found in murine transcriptomics studies, such as an increased differentiation bias towards the myeloid lineage, alterations in DNA rep...

Alternative Titles

Full title

Glucose Metabolism and Aging of Hematopoietic Stem and Progenitor Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8955027

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8955027

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms23063028

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