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Endothelial PERK-ATF4-JAG1 axis activated by T-ALL remodels bone marrow vascular niche

Endothelial PERK-ATF4-JAG1 axis activated by T-ALL remodels bone marrow vascular niche

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8965499

Endothelial PERK-ATF4-JAG1 axis activated by T-ALL remodels bone marrow vascular niche

About this item

Full title

Endothelial PERK-ATF4-JAG1 axis activated by T-ALL remodels bone marrow vascular niche

Publisher

Australia: Ivyspring International Publisher Pty Ltd

Journal title

Theranostics, 2022-01, Vol.12 (6), p.2894-2907

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher Pty Ltd

More information

Scope and Contents

Contents

The endoplasmic reticulum unfolded protein response (UPR) is a conserved adaptive signaling in ER homeostasis and has emerged as critical in highly proliferating cells and potential treatment target for acute T-cell lymphoblastic leukemia (T-ALL).
in this study, we assessed the transcriptomic and phenotypic alterations in UPR response of the bon...

Alternative Titles

Full title

Endothelial PERK-ATF4-JAG1 axis activated by T-ALL remodels bone marrow vascular niche

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8965499

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8965499

Other Identifiers

ISSN

1838-7640

E-ISSN

1838-7640

DOI

10.7150/thno.67710

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