GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas
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Author / Creator
Majzner, Robbie G. , Ramakrishna, Sneha , Yeom, Kristen W. , Patel, Shabnum , Chinnasamy, Harshini , Schultz, Liora M. , Richards, Rebecca M. , Jiang, Li , Barsan, Valentin , Mancusi, Rebecca , Geraghty, Anna C. , Good, Zinaida , Mochizuki, Aaron Y. , Gillespie, Shawn M. , Toland, Angus Martin Shaw , Mahdi, Jasia , Reschke, Agnes , Nie, Esther H. , Chau, Isabelle J. , Rotiroti, Maria Caterina , Mount, Christopher W. , Baggott, Christina , Mavroukakis, Sharon , Egeler, Emily , Moon, Jennifer , Erickson, Courtney , Green, Sean , Kunicki, Michael , Fujimoto, Michelle , Ehlinger, Zach , Reynolds, Warren , Kurra, Sreevidya , Warren, Katherine E. , Prabhu, Snehit , Vogel, Hannes , Rasmussen, Lindsey , Cornell, Timothy T. , Partap, Sonia , Fisher, Paul G. , Campen, Cynthia J. , Filbin, Mariella G. , Grant, Gerald , Sahaf, Bita , Davis, Kara L. , Feldman, Steven A. , Mackall, Crystal L. and Monje, Michelle
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Diffuse intrinsic pontine glioma (DIPG) and other H3K27M-mutated diffuse midline gliomas (DMGs) are universally lethal paediatric tumours of the central nervous system
1
. We have previously shown that the disialoganglioside GD2 is highly expressed on H3K27M-mutated glioma cells and have demonstrated promising preclinical efficacy of GD2-dire...
Alternative Titles
Full title
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas
Authors, Artists and Contributors
Author / Creator
Ramakrishna, Sneha
Yeom, Kristen W.
Patel, Shabnum
Chinnasamy, Harshini
Schultz, Liora M.
Richards, Rebecca M.
Jiang, Li
Barsan, Valentin
Mancusi, Rebecca
Geraghty, Anna C.
Good, Zinaida
Mochizuki, Aaron Y.
Gillespie, Shawn M.
Toland, Angus Martin Shaw
Mahdi, Jasia
Reschke, Agnes
Nie, Esther H.
Chau, Isabelle J.
Rotiroti, Maria Caterina
Mount, Christopher W.
Baggott, Christina
Mavroukakis, Sharon
Egeler, Emily
Moon, Jennifer
Erickson, Courtney
Green, Sean
Kunicki, Michael
Fujimoto, Michelle
Ehlinger, Zach
Reynolds, Warren
Kurra, Sreevidya
Warren, Katherine E.
Prabhu, Snehit
Vogel, Hannes
Rasmussen, Lindsey
Cornell, Timothy T.
Partap, Sonia
Fisher, Paul G.
Campen, Cynthia J.
Filbin, Mariella G.
Grant, Gerald
Sahaf, Bita
Davis, Kara L.
Feldman, Steven A.
Mackall, Crystal L.
Monje, Michelle
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8967714
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8967714
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04489-4