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GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas

GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8967714

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Diffuse intrinsic pontine glioma (DIPG) and other H3K27M-mutated diffuse midline gliomas (DMGs) are universally lethal paediatric tumours of the central nervous system
1
. We have previously shown that the disialoganglioside GD2 is highly expressed on H3K27M-mutated glioma cells and have demonstrated promising preclinical efficacy of GD2-dire...

Alternative Titles

Full title

GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8967714

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8967714

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-022-04489-4

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