Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing
Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing
About this item
Full title
Author / Creator
Ahmad, Mubashir , Krüger, Benjamin Thilo , Kroll, Torsten , Vettorazzi, Sabine , Dorn, Ann-Kristin , Mengele, Florian , Lee, Sooyeon , Nandi, Sayantan , Yilmaz, Dilay , Stolz, Miriam , Tangudu, Naveen Kumar , Vázquez, David Carro , Pachmayr, Johanna , Cirstea, Ion Cristian , Spasic, Maja Vujic , Ploubidou, Aspasia , Ignatius, Anita and Tuckermann, Jan
Publisher
China: Springer Nature B.V
Journal title
Language
English
Formats
Publication information
Publisher
China: Springer Nature B.V
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More information
Scope and Contents
Contents
Identification of regulators of osteoblastogenesis that can be pharmacologically targeted is a major goal in combating osteoporosis, a common disease of the elderly population. Here, unbiased kinome RNAi screening in primary murine osteoblasts identified cyclin-dependent kinase 5 (Cdk5) as a suppressor of osteoblast differentiation in both murine a...
Alternative Titles
Full title
Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing
Authors, Artists and Contributors
Author / Creator
Krüger, Benjamin Thilo
Kroll, Torsten
Vettorazzi, Sabine
Dorn, Ann-Kristin
Mengele, Florian
Lee, Sooyeon
Nandi, Sayantan
Yilmaz, Dilay
Stolz, Miriam
Tangudu, Naveen Kumar
Vázquez, David Carro
Pachmayr, Johanna
Cirstea, Ion Cristian
Spasic, Maja Vujic
Ploubidou, Aspasia
Ignatius, Anita
Tuckermann, Jan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8983726
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8983726
Other Identifiers
ISSN
2095-4700
E-ISSN
2095-6231
DOI
10.1038/s41413-022-00195-z
