Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine
Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine
About this item
Full title
Author / Creator
Li, Chunfeng , Lee, Audrey , Grigoryan, Lilit , Arunachalam, Prabhu S. , Scott, Madeleine K. D. , Trisal, Meera , Wimmers, Florian , Sanyal, Mrinmoy , Weidenbacher, Payton A. , Feng, Yupeng , Adamska, Julia Z. , Valore, Erika , Wang, Yanli , Verma, Rohit , Reis, Noah , Dunham, Diane , O’Hara, Ruth , Park, Helen , Luo, Wei , Gitlin, Alexander D. , Kim, Peter , Khatri, Purvesh , Nadeau, Kari C. and Pulendran, Bali
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Despite the success of the BNT162b2 mRNA vaccine, the immunological mechanisms that underlie its efficacy are poorly understood. Here we analyzed the innate and adaptive responses to BNT162b2 in mice, and show that immunization stimulated potent antibody and antigen-specific T cell responses, as well as strikingly enhanced innate responses after se...
Alternative Titles
Full title
Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine
Authors, Artists and Contributors
Author / Creator
Lee, Audrey
Grigoryan, Lilit
Arunachalam, Prabhu S.
Scott, Madeleine K. D.
Trisal, Meera
Wimmers, Florian
Sanyal, Mrinmoy
Weidenbacher, Payton A.
Feng, Yupeng
Adamska, Julia Z.
Valore, Erika
Wang, Yanli
Verma, Rohit
Reis, Noah
Dunham, Diane
O’Hara, Ruth
Park, Helen
Luo, Wei
Gitlin, Alexander D.
Kim, Peter
Khatri, Purvesh
Nadeau, Kari C.
Pulendran, Bali
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8989677
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8989677
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-022-01163-9
