Nivolumab plus ipilimumab with or without live bacterial supplementation in metastatic renal cell ca...
Nivolumab plus ipilimumab with or without live bacterial supplementation in metastatic renal cell carcinoma: a randomized phase 1 trial
About this item
Full title
Author / Creator
Dizman, Nazli , Meza, Luis , Bergerot, Paulo , Alcantara, Marice , Dorff, Tanya , Lyou, Yung , Frankel, Paul , Cui, Yujie , Mira, Valerie , Llamas, Marian , Hsu, Joann , Zengin, Zeynep , Salgia, Nicholas , Salgia, Sabrina , Malhotra, Jasnoor , Chawla, Neal , Chehrazi-Raffle, Alex , Muddasani, Ramya , Gillece, John , Reining, Lauren , Trent, Jeff , Takahashi, Motomichi , Oka, Kentaro , Higashi, Seiya , Kortylewski, Marcin , Highlander, Sarah K. and Pal, Sumanta K.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Previous studies have suggested that the gut microbiome influences the response to checkpoint inhibitors (CPIs) in patients with cancer. CBM588 is a bifidogenic live bacterial product that we postulated could augment CPI response through modulation of the gut microbiome. In this open-label, single-center study (NCT03829111), 30 treatment-naive pati...
Alternative Titles
Full title
Nivolumab plus ipilimumab with or without live bacterial supplementation in metastatic renal cell carcinoma: a randomized phase 1 trial
Authors, Artists and Contributors
Author / Creator
Meza, Luis
Bergerot, Paulo
Alcantara, Marice
Dorff, Tanya
Lyou, Yung
Frankel, Paul
Cui, Yujie
Mira, Valerie
Llamas, Marian
Hsu, Joann
Zengin, Zeynep
Salgia, Nicholas
Salgia, Sabrina
Malhotra, Jasnoor
Chawla, Neal
Chehrazi-Raffle, Alex
Muddasani, Ramya
Gillece, John
Reining, Lauren
Trent, Jeff
Takahashi, Motomichi
Oka, Kentaro
Higashi, Seiya
Kortylewski, Marcin
Highlander, Sarah K.
Pal, Sumanta K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9018425
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9018425
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-022-01694-6
