Inhibiting Hv1 channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid...
Inhibiting Hv1 channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid side effects
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Author / Creator
Zhang, Qiansen , Ren, Yimin , Mo, Yiqing , Guo, Peipei , Liao, Ping , Luo, Yuncheng , Mu, Jie , Chen, Zhuo , Zhang, Yang , Li, Ya , Yang, Linghui , Liao, Daqing , Fu, Jie , Shen, Juwen , Huang, Wei , Xu, Xuewen , Guo, Yanyan , Mei, Lianghe , Zuo, Yunxia , Liu, Jin , Yang, Huaiyu and Jiang, Ruotian
Publisher
Singapore: Springer Nature Singapore
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Language
English
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Publisher
Singapore: Springer Nature Singapore
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Scope and Contents
Contents
Both opioids and nonsteroidal anti-inflammatory drugs (NSAIDS) produce deleterious side effects and fail to provide sustained relief in patients with chronic inflammatory pain. Peripheral neuroinflammation (PN) is critical for initiation and development of inflammatory pain. A better understanding of molecular mechanisms underlying PN would facilit...
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Full title
Inhibiting Hv1 channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid side effects
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9061814
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9061814
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ISSN
1748-7838,1001-0602
E-ISSN
1748-7838
DOI
10.1038/s41422-022-00616-y