Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activat...
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK
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Author / Creator
Chen, Cheng , Chen, Yaohua , Liu, Tingting , Song, Dan , Ma, Di and Cheng, Oumei
Publisher
United States: Hindawi
Journal title
Language
English
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Publication information
Publisher
United States: Hindawi
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Scope and Contents
Contents
Parkinson’s disease (PD) is a common neurodegenerative disease characterized by the degeneration of dopaminergic (DA) neurons in the substantia nigra (SN). Our previous study has shown that dexmedetomidine (Dex) can protect mitochondrial function and reduce apoptosis in MPP+-induced SH-SY5Y cells. Evidences have shown that mitophagy is related to t...
Alternative Titles
Full title
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9068320
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9068320
Other Identifiers
ISSN
1942-0900
E-ISSN
1942-0994
DOI
10.1155/2022/7511393