Single-cell genomic profiling of human dopamine neurons identifies a population that selectively deg...
Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The loss of dopamine (DA) neurons within the substantia nigra pars compacta (SNpc) is a defining pathological hallmark of Parkinson’s disease (PD). Nevertheless, the molecular features associated with DA neuron vulnerability have not yet been fully identified. Here, we developed a protocol to enrich and transcriptionally profile DA neurons from pat...
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Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9076534
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9076534
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ISSN
1097-6256,1546-1726
E-ISSN
1546-1726
DOI
10.1038/s41593-022-01061-1
