PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38MAPK signalling
PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38MAPK signalling
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Glioblastoma (GBM) is the most common and fatal primary brain tumour in adults. Considering that resistance to current therapies leads to limited response in patients, new therapeutic options are urgently needed. In recent years, differentiation therapy has been proposed as an alternative for GBM treatment, with the aim of bringing cancer cells int...
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PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38MAPK signalling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9076540
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9076540
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-022-02294-x