Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation
Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The NLRP3 inflammasome is linked to sterile and pathogen-dependent inflammation, and its dysregulation underlies many chronic diseases. Mitochondria have been implicated as regulators of the NLRP3 inflammasome through several mechanisms including generation of mitochondrial reactive oxygen species (ROS). Here, we report that mitochondrial electron...
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Full title
Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9098388
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9098388
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ISSN
1529-2908,1529-2916
E-ISSN
1529-2916
DOI
10.1038/s41590-022-01185-3
