Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease...
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity
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Author / Creator
Uzzan, Mathieu , Martin, Jerome C. , Mesin, Luka , Livanos, Alexandra E. , Castro-Dopico, Tomas , Huang, Ruiqi , Petralia, Francesca , Magri, Giuliana , Kumar, Shashi , Zhao, Qing , Rosenstein, Adam K. , Tokuyama, Minami , Sharma, Keshav , Ungaro, Ryan , Kosoy, Roman , Jha, Divya , Fischer, Jeremy , Singh, Harpriya , Keir, Mary E. , Ramamoorthi, Nandhini , O’Gorman, William E. , Cohen, Benjamin L. , Rahman, Adeeb , Cossarini, Francesca , Seki, Akihiro , Leyre, Louise , Vaquero, Sonia Tejedor , Gurunathan, Sakteesh , Grasset, Emilie K. , Losic, Bojan , Dubinsky, Marla , Greenstein, Alexander J. , Gottlieb, Zoe , Legnani, Peter , George, James , Irizar, Haritz , Stojmirovic, Aleksandar , Brodmerkel, Carrie , Kasarkis, Andrew , Sands, Bruce E. , Furtado, Glaucia , Lira, Sergio A. , Tuong, Zewen K. , Ko, Huaibin M. , Cerutti, Andrea , Elson, Charles O. , Clatworthy, Menna R. , Merad, Miriam , Suárez-Fariñas, Mayte , Argmann, Carmen , Hackney, Jason A. , Victora, Gabriel D. , Randolph, Gwendalyn J. , Kenigsberg, Ephraim , Colombel, Jean Frederic and Mehandru, Saurabh
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
B cells, which are critical for intestinal homeostasis, remain understudied in ulcerative colitis (UC). In this study, we recruited three cohorts of patients with UC (primary cohort,
n
= 145; validation cohort 1,
n
= 664; and validation cohort 2,
n
= 143) to comprehensively define the landscape of B cells during UC-associated i...
Alternative Titles
Full title
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity
Authors, Artists and Contributors
Author / Creator
Martin, Jerome C.
Mesin, Luka
Livanos, Alexandra E.
Castro-Dopico, Tomas
Huang, Ruiqi
Petralia, Francesca
Magri, Giuliana
Kumar, Shashi
Zhao, Qing
Rosenstein, Adam K.
Tokuyama, Minami
Sharma, Keshav
Ungaro, Ryan
Kosoy, Roman
Jha, Divya
Fischer, Jeremy
Singh, Harpriya
Keir, Mary E.
Ramamoorthi, Nandhini
O’Gorman, William E.
Cohen, Benjamin L.
Rahman, Adeeb
Cossarini, Francesca
Seki, Akihiro
Leyre, Louise
Vaquero, Sonia Tejedor
Gurunathan, Sakteesh
Grasset, Emilie K.
Losic, Bojan
Dubinsky, Marla
Greenstein, Alexander J.
Gottlieb, Zoe
Legnani, Peter
George, James
Irizar, Haritz
Stojmirovic, Aleksandar
Brodmerkel, Carrie
Kasarkis, Andrew
Sands, Bruce E.
Furtado, Glaucia
Lira, Sergio A.
Tuong, Zewen K.
Ko, Huaibin M.
Cerutti, Andrea
Elson, Charles O.
Clatworthy, Menna R.
Merad, Miriam
Suárez-Fariñas, Mayte
Argmann, Carmen
Hackney, Jason A.
Victora, Gabriel D.
Randolph, Gwendalyn J.
Kenigsberg, Ephraim
Colombel, Jean Frederic
Mehandru, Saurabh
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9107072
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9107072
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X,1744-7933
DOI
10.1038/s41591-022-01680-y
