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Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43

Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9107452

Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43

About this item

Full title

Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2022-06, Vol.143 (6), p.613-640

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Intracellular accumulation of abnormal proteins with conformational changes is the defining neuropathological feature of neurodegenerative diseases. The pathogenic proteins that accumulate in patients' brains adopt an amyloid-like fibrous structure and exhibit various ultrastructural features. The biochemical analysis of pathogenic proteins in sark...

Alternative Titles

Full title

Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9107452

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9107452

Other Identifiers

ISSN

0001-6322,1432-0533

E-ISSN

1432-0533

DOI

10.1007/s00401-022-02426-3

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