Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin ada...
Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability
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Author / Creator
Guo, Peipei , Liu, Ying , Geng, Fuqiang , Daman, Andrew W. , Liu, Xiaoyu , Zhong, Liangwen , Ravishankar, Arjun , Lis, Raphael , Barcia Durán, José Gabriel , Itkin, Tomer , Tang, Fanying , Zhang, Tuo , Xiang, Jenny , Shido, Koji , Ding, Bi-sen , Wen, Duancheng , Josefowicz, Steven Z. and Rafii, Shahin
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Histone variants and the associated post-translational modifications that govern the stemness of haematopoietic stem cells (HSCs) and differentiation thereof into progenitors (HSPCs) have not been well defined. H3.3 is a replication-independent H3 histone variant in mammalian systems that is enriched at both H3K4me3- and H3K27me3-marked bivalent ge...
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Full title
Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9166935
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9166935
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ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/s41556-021-00795-7