A gut-derived metabolite alters brain activity and anxiety behaviour in mice
A gut-derived metabolite alters brain activity and anxiety behaviour in mice
About this item
Full title
Author / Creator
Needham, Brittany D. , Funabashi, Masanori , Adame, Mark D. , Wang, Zhuo , Boktor, Joseph C. , Haney, Jillian , Wu, Wei-Li , Rabut, Claire , Ladinsky, Mark S. , Hwang, Son-Jong , Guo, Yumei , Zhu, Qiyun , Griffiths, Jessica A. , Knight, Rob , Bjorkman, Pamela J. , Shapiro, Mikhail G. , Geschwind, Daniel H. , Holschneider, Daniel P. , Fischbach, Michael A. and Mazmanian, Sarkis K.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Integration of sensory and molecular inputs from the environment shapes animal behaviour. A major site of exposure to environmental molecules is the gastrointestinal tract, in which dietary components are chemically transformed by the microbiota
1
and gut-derived metabolites are disseminated to all organs, including the brain
2
. In mic...
Alternative Titles
Full title
A gut-derived metabolite alters brain activity and anxiety behaviour in mice
Authors, Artists and Contributors
Author / Creator
Funabashi, Masanori
Adame, Mark D.
Wang, Zhuo
Boktor, Joseph C.
Haney, Jillian
Wu, Wei-Li
Rabut, Claire
Ladinsky, Mark S.
Hwang, Son-Jong
Guo, Yumei
Zhu, Qiyun
Griffiths, Jessica A.
Knight, Rob
Bjorkman, Pamela J.
Shapiro, Mikhail G.
Geschwind, Daniel H.
Holschneider, Daniel P.
Fischbach, Michael A.
Mazmanian, Sarkis K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9170029
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9170029
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04396-8