Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T...
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation
About this item
Full title
Author / Creator
Yshii, Lidia , Pasciuto, Emanuela , Bielefeld, Pascal , Mascali, Loriana , Lemaitre, Pierre , Marino, Marika , Dooley, James , Kouser, Lubna , Verschoren, Stijn , Lagou, Vasiliki , Kemps, Hannelore , Gervois, Pascal , de Boer, Antina , Burton, Oliver T. , Wahis, Jérôme , Verhaert, Jens , Tareen, Samar H. K. , Roca, Carlos P. , Singh, Kailash , Whyte, Carly E. , Kerstens, Axelle , Callaerts-Vegh, Zsuzsanna , Poovathingal, Suresh , Prezzemolo, Teresa , Wierda, Keimpe , Dashwood, Amy , Xie, Junhua , Van Wonterghem, Elien , Creemers, Eline , Aloulou, Meryem , Gsell, Willy , Abiega, Oihane , Munck, Sebastian , Vandenbroucke, Roosmarijn E. , Bronckaers, Annelies , Lemmens, Robin , De Strooper, Bart , Van Den Bosch, Ludo , Himmelreich, Uwe , Fitzsimons, Carlos P. , Holt, Matthew G. and Liston, Adrian
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The ability of immune-modulating biologics to prevent and reverse pathology has transformed recent clinical practice. Full utility in the neuroinflammation space, however, requires identification of both effective targets for local immune modulation and a delivery system capable of crossing the blood–brain barrier. The recent identification and cha...
Alternative Titles
Full title
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation
Authors, Artists and Contributors
Author / Creator
Pasciuto, Emanuela
Bielefeld, Pascal
Mascali, Loriana
Lemaitre, Pierre
Marino, Marika
Dooley, James
Kouser, Lubna
Verschoren, Stijn
Lagou, Vasiliki
Kemps, Hannelore
Gervois, Pascal
de Boer, Antina
Burton, Oliver T.
Wahis, Jérôme
Verhaert, Jens
Tareen, Samar H. K.
Roca, Carlos P.
Singh, Kailash
Whyte, Carly E.
Kerstens, Axelle
Callaerts-Vegh, Zsuzsanna
Poovathingal, Suresh
Prezzemolo, Teresa
Wierda, Keimpe
Dashwood, Amy
Xie, Junhua
Van Wonterghem, Elien
Creemers, Eline
Aloulou, Meryem
Gsell, Willy
Abiega, Oihane
Munck, Sebastian
Vandenbroucke, Roosmarijn E.
Bronckaers, Annelies
Lemmens, Robin
De Strooper, Bart
Van Den Bosch, Ludo
Himmelreich, Uwe
Fitzsimons, Carlos P.
Holt, Matthew G.
Liston, Adrian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9174055
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9174055
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-022-01208-z
