Development of spirulina for the manufacture and oral delivery of protein therapeutics
Development of spirulina for the manufacture and oral delivery of protein therapeutics
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Author / Creator
Sandia National Lab. (SNL-CA), Livermore, CA (United States) , Jester, Benjamin W. , Zhao, Hui , Gewe, Mesfin , Adame, Thomas , Perruzza, Lisa , Bolick, David T. , Agosti, Jan , Khuong, Nhi , Kuestner, Rolf , Gamble, Caitlin , Cruickshank, Kendra , Ferrara, Jeremy , Lim, Rachelle , Paddock, Troy , Brady, Colin , Ertel, Stacey , Zhang, Miaohua , Pollock, Alex , Lee, Jamie , Xiong, Jian , Tasch, Michael , Saveria, Tracy , Doughty, David , Marshall, Jacob , Carrieri, Damian , Goetsch, Lauren , Dang, Jason , Sanjaya, Nathaniel , Fletcher, David , Martinez, Anissa , Kadis, Bryce , Sigmar, Kristjan , Afreen, Esha , Nguyen, Tammy , Randolph, Amanda , Taber, Alexandria , Krzeszowski, Ashley , Robinett, Brittney , Volkin, David B. , Grassi, Fabio , Guerrant, Richard , Takeuchi, Ryo , Finrow, Brian , Behnke, Craig and Roberts, James
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The use of the edible photosynthetic cyanobacterium
Arthrospira platensis
(spirulina) as a biomanufacturing platform has been limited by a lack of genetic tools. Here we report genetic engineering methods for stable, high-level expression of bioactive proteins in spirulina, including large-scale, indoor cultivation and downstream processing m...
Alternative Titles
Full title
Development of spirulina for the manufacture and oral delivery of protein therapeutics
Authors, Artists and Contributors
Author / Creator
Jester, Benjamin W.
Zhao, Hui
Gewe, Mesfin
Adame, Thomas
Perruzza, Lisa
Bolick, David T.
Agosti, Jan
Khuong, Nhi
Kuestner, Rolf
Gamble, Caitlin
Cruickshank, Kendra
Ferrara, Jeremy
Lim, Rachelle
Paddock, Troy
Brady, Colin
Ertel, Stacey
Zhang, Miaohua
Pollock, Alex
Lee, Jamie
Xiong, Jian
Tasch, Michael
Saveria, Tracy
Doughty, David
Marshall, Jacob
Carrieri, Damian
Goetsch, Lauren
Dang, Jason
Sanjaya, Nathaniel
Fletcher, David
Martinez, Anissa
Kadis, Bryce
Sigmar, Kristjan
Afreen, Esha
Nguyen, Tammy
Randolph, Amanda
Taber, Alexandria
Krzeszowski, Ashley
Robinett, Brittney
Volkin, David B.
Grassi, Fabio
Guerrant, Richard
Takeuchi, Ryo
Finrow, Brian
Behnke, Craig
Roberts, James
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9200632
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9200632
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-022-01249-7