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Limited Dose-Dependent Effects of Vedolizumab on Various Leukocyte Subsets

Limited Dose-Dependent Effects of Vedolizumab on Various Leukocyte Subsets

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9236604

Limited Dose-Dependent Effects of Vedolizumab on Various Leukocyte Subsets

About this item

Full title

Limited Dose-Dependent Effects of Vedolizumab on Various Leukocyte Subsets

Publisher

United States: Wolters Kluwer

Journal title

Clinical and translational gastroenterology, 2022-06, Vol.13 (6), p.e00494-e00494

Language

English

Formats

Publication information

Publisher

United States: Wolters Kluwer

More information

Scope and Contents

Contents

The anti-α4β7 integrin antibody vedolizumab (VDZ) is successfully used for the treatment of inflammatory bowel diseases. However, only a subgroup of patients respond to therapy. VDZ is administered at a fixed dose, leading to a wide range of serum concentrations in patients. Previous work from our group showed a dose-dependent preferential binding...

Alternative Titles

Full title

Limited Dose-Dependent Effects of Vedolizumab on Various Leukocyte Subsets

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9236604

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9236604

Other Identifiers

ISSN

2155-384X

E-ISSN

2155-384X

DOI

10.14309/ctg.0000000000000494

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