Genetic analysis of the human microglia transcriptome across brain regions, aging and disease pathol...
Genetic analysis of the human microglia transcriptome across brain regions, aging and disease pathologies
About this item
Full title
Author / Creator
de Paiva Lopes, Katia , Snijders, Gijsje J. L. , Humphrey, Jack , Allan, Amanda , Sneeboer, Marjolein , Navarro, Elisa , Schilder, Brian M. , Vialle, Ricardo A. , Parks, Madison , Missall, Roy , van Zuiden, Welmoed , Gigase, Frederieke , Kübler, Raphael , van Berlekom, Amber Berdenis , Hicks, Emily M. , Bӧttcher, Chotima , Priller, Josef , Kahn, René S. , de Witte, Lot D. and Raj, Towfique
Journal title
Language
English
Formats
More information
Scope and Contents
Contents
Microglia have emerged as important players in brain aging and pathology. To understand how genetic risk for neurological and psychiatric disorders is related to microglial function, large transcriptome studies are essential. Here, we describe the transcriptome analysis of 255 primary human microglia samples isolated at autopsy from multiple brain...
Alternative Titles
Full title
Genetic analysis of the human microglia transcriptome across brain regions, aging and disease pathologies
Authors, Artists and Contributors
Author / Creator
Snijders, Gijsje J. L.
Humphrey, Jack
Allan, Amanda
Sneeboer, Marjolein
Navarro, Elisa
Schilder, Brian M.
Vialle, Ricardo A.
Parks, Madison
Missall, Roy
van Zuiden, Welmoed
Gigase, Frederieke
Kübler, Raphael
van Berlekom, Amber Berdenis
Hicks, Emily M.
Bӧttcher, Chotima
Priller, Josef
Kahn, René S.
de Witte, Lot D.
Raj, Towfique
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9245609
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9245609
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-021-00976-y