Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast
Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast
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United States: The American Society for Cell Biology
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English
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United States: The American Society for Cell Biology
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Cdc42, a conserved Rho GTPase, plays a central role in polarity establishment in yeast and animals. Cell polarity is critical for asymmetric cell division, and asymmetric cell division underlies replicative aging of budding yeast. Yet how Cdc42 and other polarity factors impact life span is largely unknown. Here we show by live-cell imaging that th...
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Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9250358
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9250358
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ISSN
1059-1524
E-ISSN
1939-4586
DOI
10.1091/mbc.E21-04-0208