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Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast

Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9250358

Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast

About this item

Full title

Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast

Publisher

United States: The American Society for Cell Biology

Journal title

Molecular biology of the cell, 2022-04, Vol.33 (4), p.br5-br5

Language

English

Formats

Publication information

Publisher

United States: The American Society for Cell Biology

More information

Scope and Contents

Contents

Cdc42, a conserved Rho GTPase, plays a central role in polarity establishment in yeast and animals. Cell polarity is critical for asymmetric cell division, and asymmetric cell division underlies replicative aging of budding yeast. Yet how Cdc42 and other polarity factors impact life span is largely unknown. Here we show by live-cell imaging that th...

Alternative Titles

Full title

Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9250358

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9250358

Other Identifiers

ISSN

1059-1524

E-ISSN

1939-4586

DOI

10.1091/mbc.E21-04-0208

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